Science and evidence

The science behind PetdentistCare™

Every claim graded, every study named, and nothing learned in dogs borrowed for cats. This is how our science works, what it knows, and where it stops.

Short answer: PetdentistCare™ grades the evidence behind every scientific statement from A (a controlled trial of the exact product, in the species it is sold for) to E (a theoretical rationale), and the strength of a claim never exceeds the strength of its evidence. Dogs, cats and horses have very different mouths, so each species gets its own evidence. Biodontic™, our science division, maps and grades the research; Odovyx™, our ingredient technology platform, turns it into safety-reviewed ingredient choices; and our Science & Compliance Office checks every word before it is published.

Why we grade evidence from A to E

Pet oral-care marketing often quotes a laboratory dish, a study in people and a trial in dogs in the same breath, as if they proved the same thing. They do not, so we grade.

A grade tells you how directly the evidence applies to the statement beside it. A means a controlled trial of the exact finished product, in the species it is sold for. B means a strain- or species-specific study in dogs or cats. C is species mechanistic evidence, such as how the microbes in a dog's mouth change as gums become unhealthy. D is laboratory (in-vitro) work. E is a sensible idea not yet tested.

One rule follows: the strength of a claim never exceeds the strength of its evidence. Results in people are never used for pets, results in dogs are never used for cats, and one strain's results never stand in for another's. Read the full evidence standard.

Three mouths compared: dogs, cats and horses

Most mistakes in pet oral care start with a false assumption: that a dog's mouth works like ours, or that a cat's works like a dog's. Here are the three species side by side.

FeatureDogsCatsHorses
Adult teeth423036 to 44, varying between individuals
How the teeth growA fixed adult set, through by around six to seven monthsA fixed adult set, through by around six monthsLong-crowned (hypsodont) cheek teeth that keep erupting throughout life
SalivaAlkaline, around pH 7.5 to 8.5Alkaline, around pH 7.5 to 8.5To be confirmed
EnamelThin: about 0.1 to 0.6 mmThin: about 0.1 to 0.6 mmTo be confirmed
Plaque to tartarSoft plaque can begin to harden within about 48 to 72 hoursSoft plaque can begin to harden within about 48 to 72 hoursTo be confirmed
What vets look forPlaque and tartar at the gumline, periodontal disease, broken teeth (especially the large upper cheek teeth), retained baby teeth and crowding in short-muzzled breedsPeriodontal disease, tooth resorption and stomatitis; cats hide discomfort, so changes are easy to missSharp enamel points and hooks, diastemata (gaps where food packs), periodontal disease, peripheral caries and, in older horses, equine odontoclastic tooth resorption and hypercementosis (EOTRH)
How common (UK studies)12.5% diagnosed with periodontal disease in a year15.2% diagnosed with periodontal disease in a yearPeriodontal disease in 13.9% and diastemata in 8.7% of 932 horses
UK populationAbout 15.5 millionAbout 13 millionAbout 600,000 horses and ponies
Professional careA veterinary surgeonA veterinary surgeonVeterinary surgeons and, in the UK, BAEDT/BEVA-qualified equine dental technicians

Sources: Petdentist® comparative oral-biology notes; Royal Veterinary College VetCompass studies of dogs (2021) and cats (O'Neill and colleagues, 2023); a UK first-opinion equine study (Suthers and colleagues, 2019); UK Pet Food population data (January 2026). The prevalence figures come from different study designs and should not be compared directly. Where our review is not complete, we say “to be confirmed” rather than guess.

For comparison, people have 32 adult teeth, saliva closer to pH 6.5 to 7.0 and enamel about 2 to 2.5 mm thick. That is why dogs and cats rarely get the cavities we do but build tartar quickly, and why human toothpaste has no place in a pet's mouth.

The oral microbiome: what we know, and what we don't

Every mouth carries a community of microbes. In dogs and cats most of it lives in biofilm: the soft, sticky film we call plaque, which re-forms constantly and is thickest along the gumline.

Reasonably well established

  • Dogs and cats each carry their own oral microbial community, distinct from each other's and from ours C.
  • In both species the community differs between healthy and unhealthy mouths C. In dogs, published studies describe a shift towards groups such as Porphyromonas (notably Porphyromonas gulae), Prevotella, Treponema, Tannerella and Fusobacterium as gums become unhealthy C.
  • A few specific probiotic strains and heat-inactivated preparations have been studied in small, short-term trials: in dogs with plaque-related and microbial measures, and in cats with microbial measures only B for those exact strains.

Still unknown

  • What a healthy oral community looks like for an individual pet, and whether the shift mainly drives gum changes, follows them, or both.
  • Whether any product changes the community in a way that lasts, and how much it adds for a pet whose teeth are cleaned every day.
  • How any of this applies to horses and camels. We have not yet reviewed their oral-microbiome research, and we assume nothing from dogs or cats.

What is known points to one aim for daily care: balance, not sterility. Read the full guide to the oral microbiome.

How Biodontic™ and Odovyx™ work together

Biodontic™ is Petdentist's science division: the science of a healthier oral biome. Odovyx™ is our ingredient technology platform, where nature meets advanced oral care. They answer different questions, in a fixed order.

Map

Biodontic™ builds a structured map of the literature, from the canine and feline oral microbiome to plaque, calculus and breath, and grades each finding.

Select

Odovyx™ chooses ingredients only where evidence, species safety and format agree, and documents every raw material.

Test

Safety, stability and palatability come first. A claim that needs it waits for a controlled trial of the exact product, designed before it starts.

Review

The Science & Compliance Office checks every word against the evidence grade and the rules of each market.

Publish

Findings go into the research library with their grade and limits, and pages are updated as the evidence changes.

An independent scientific advisory board, now being recruited, will challenge each stage. Neither division makes a claim the evidence has not earned, and neither publishes formulations.

Where our science stops

We are a pet oral-care company, not a veterinary practice. Our founder, Dr Deepak Songra, is a human dental surgeon, not a veterinary surgeon. Our education explains how mouths work, what vets look for and when to see one; it never diagnoses an individual animal, and no product on this platform is a medicine.

The honest limits matter as much as the findings. Most pet oral-microbiome research is recent, small and short, and we would rather tell you so than sell around it.

When to see your vet

If you notice loose or wobbly teeth, swelling, discharge, bleeding that does not settle, reluctance to eat, dropping food, drooling, pawing at the mouth or any change in behaviour, please contact your veterinary surgeon promptly. Home care supports professional care — it never replaces it.

How we grade evidence

Every scientific statement on this site carries a grade: A product-specific controlled trial · B strain- or species-specific study in dogs or cats · C species mechanistic evidence · D laboratory (in-vitro) evidence · E theoretical rationale. The strength of a claim never exceeds the strength of its evidence. Read our evidence standards.

Questions people ask

Frequently asked questions

What does “evidence-graded” mean on PetdentistCare™?

It means each scientific statement is labelled with how directly the evidence supports it, from A, a controlled trial of the exact product in that species, to E, a theoretical rationale that has not yet been tested. The grade sits beside the statement, and the strength of any claim we make never exceeds it. The full method is on our evidence standards page.

Why don't you use dog studies for cats?

Because cats are not small dogs. They have different teeth, their own oral microbial community and a different metabolism, including a limited ability to process phenols and many essential oils. A result in dogs tells us nothing reliable about cats, so statements about cats rest on cat evidence, and we say plainly when that evidence is thin.

Is Biodontic™ a product range?

No. Biodontic™ is the name of Petdentist's science division. It maps and grades published research, builds evidence dossiers on ingredients, designs studies and supports the independent scientific advisory board. Nothing on this site should be read as promising a product under that name.

What does Odovyx™ do?

Odovyx™ is our ingredient technology platform. It selects and documents the ingredients used in daily oral-care products, reviewing each one for species safety, format and regulatory status in every market. We explain which categories of ingredient we use and why, but we do not publish formulations, and Odovyx™ makes no efficacy claims for ingredients on their own.

Do dogs, cats and horses need the same oral care?

No. Dogs and cats have a fixed set of adult teeth and alkaline saliva, so soft plaque can begin to harden into tartar within about 48 to 72 hours, and daily cleaning along the gumline matters most. Horses' cheek teeth keep erupting throughout life and need regular checks by a vet or a qualified equine dental technician. Every product should be made for the species using it.

Does Petdentist® run its own studies?

None has been published yet. Biodontic™ is building a staged programme: a map of the published literature, evidence dossiers for each ingredient, laboratory screening where it is justified, safety and palatability work, and then controlled trials of exact products. When a Petdentist® study is completed, it will be listed in our research library with its methods, grade and limitations.

Who checks the science on this site?

Every page is drafted with named sources, graded against our A to E standard and reviewed by the Petdentist® Science & Compliance Office for accuracy and for UK, UAE and other market rules before it is published. An independent scientific advisory board is being recruited. Our founder is a human dental surgeon, not a veterinary surgeon, and his byline says so.

Can PetdentistCare™ tell me what is wrong with my pet's mouth?

No. Our education explains how mouths work and what vets look for, but only a veterinary surgeon can examine, diagnose and advise on an individual animal. If you notice loose or broken teeth, swelling, bleeding, a change in eating or strong new breath, please contact your vet promptly.

Evidence over hype

See exactly how we grade a claim

The A to E standard, the claims lexicon and the VOHC seal, explained in plain English.

Read our evidence standards